Eat more seafood, it is good for you!

The longer fatty acids, EPA, DPA and DHA, are the so-called marine omega-3 fatty acids. As the name implies these are in seafood. These fatty acids are produced by krill, which in turn are eaten by fish. Krill, oily fish, and mammals that feed on fish such as seals and whales, are good sources of these fatty acids. Oils extracted from these, such as krill oil, cod liver oil, salmon oil and seal oil are good sources. Farmed fish are eating much less krill than wild fish, because they are fed with concentrates added soy oil. This is reflected in the omega-3 content of the fish, where the omega-3 levels are lower and omega-6 levels are higher. Anyhow, farmed fish still have a beneficial omega-6 : omega-3 ratio.

A proper ratio of omega-6 and omega-3 fatty acids in food is important. This is because  the hormone-like signal substances called prostaglandins are formed from these fatty acids. There are bad prostaglandins (series-2 prostaglandins) which exacerbates inflammation and pain sensation, and good prostaglandins (series-1 and series-3-prostaglandins) that counteracts inflammation and pain sensation. Series-2 prostaglandins are formed from arachidonic acid (AA) which is an omega-6 fatty acid. Series-1 prostaglandins are made from di-homo-gamma-linolenic acid (DGLA) also an omega-6 fatty acid, and series-3-prostaglandins are formed from eicosapentaenoic acid (EPA) an omega-3 fatty acid.

For the body to make the most of the good series-1 and series-3 prostaglandins the ratio of the omega-6 and omega-3 should be in the range of 1:1 to 4:1. For most people today this ratio is approximately 20:1. By replacing some items in the diet and skip some foods, you will be able to improve this ratio.

Functionally, the prostaglandins are similar to hormones, but hormones are produced in specialized glands, while prostaglandins are produced in small quantities in all body cells and tissues. Hormones are transported by the blood to the target cells, while the prostaglandins have a local effect where they are produced.

Prostaglandins have several different functions, most important for us with Endometriosis is the prostaglandin-serie 2E (PGE2). PGE2 lead to increased pain sensation and inflammation, it induce increased estrogen synthesis and it alter the body’s thermostat and cause fever.

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